NVF webinar 7th of December 2022, 16:00 CET, Prof. dr. Sébastien Foulquier and João Faria.

Dear all,
We invite you to the next NVF meeting organized by the Dutch Pharmacology Society.
During this meeting you will have the chance to participate in the lecture of Prof. dr. Sébastien Foulquier and PhD student João Faria.


Speaker 1: Dr Sébastien Foulquier, Pharm.D., Assistant Professor, Dept. of Pharmacology- Toxicology, Maastricht University
Title of the talk: Hypoxic signaling in oligodendrocyte precursor
cells: relevance for cerebral small vessel disease
Short summary: White matter lesions are a hallmark of cerebral small vessel disease. Imaging studies have shown their association with decreased cerebral blood flow and increased blood brain barrier permeability. In this lecture, I will highlight the impact of hypoxia on oligodendrocyte precursor cells and how this may affect the cerebral small vessels.

Speaker 2: PhD student, João Faria, Dept. of Pharmaceutical Sciences, Utrecht Institute for Pharmaceutical Sciences
Title of the talk: Efficacy of mesenchymal stromal cells in ameliorating renal ischemia-reperfusion injury in vitro
Short summary:  Kidney ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care is focuse on treatments to support kidney function, stating the need for more efficient and specific therapies aiming to revert the injury. Mesenchymal stromal cells (MSCs) have been proposed as a novel cell-based regenerative therapy, showing promising results in several preclinical applications. However, its full potential in AKI is still unknown. In this talk, I will describe an in vitro model that can replicate key IRI features and discuss the role of MSCs in treating this type of injury.