The Ariëns lecture is an annual event at the FIGON Dutch Medicine days, organized by the Dutch Pharmacological Society since 1984. This lecture is named after the famous Dutch pharmacologist Prof. Dr. E.J. Ariëns (1918-2002), one of the founding fathers of the receptor theory. Herewith the Dutch Pharmacological Society recognizes the importance of the work of Professor Ariëns as the founder of pharmacology in the Netherlands and the importance of pharmacology as an essential component in the development of new medicines. After the lecture, the Ariëns price is handed over to the lecturer to commemorate the event. Ariëns lecturers are eminent pharmacologists with a strong international orientation and a focus on molecular pharmacology, in the spirit of the legacy of Prof. Ariëns. Candidates can be nominated by the members of the Dutch Pharmacological Society and are evaluated by the selection committee of our Society. Selection criteria are:
- the quantity and the scientific quality of the candidate’s work
- the focus on molecular interactions
- international orientation of the candidate
Nomination deadline: 1 st of March 2021
Ariens award 2020
This year 2020, the laureate is Prof. dr. Malcolm Rowland. This Ariens lecture was entitled: “Physiologically-Based Pharmacokinetic modelling”.
Malcolm Rowland is member and former director (1996-2000) of the Centre for Applied Pharmacokinetic Research, University of Manchester, U.K, and Adjunct Professor, Department of Bioengineering and Therapeutic Sciences, University of California San Francisco (UCSF). He was President, EUFEPS (European Federation for Pharmaceutical Sciences,1996-2000); and a Vicepresident FIP (International Pharmaceutical Federation, 2001- 2009). Dr. Rowland has been a frontrunner in basic and theoretical aspects of pharmacokinetics, especially physiologic pharmacokinetics. His main research interest is physiologically based pharmacokinetics and its application to drug discovery, development and use. He is also strongly associated with clearance concepts in pharmacokinetics. Author of over 300 scientific articles, and co-author, with Dr. TN Tozer, of the textbooks: Clinical Pharmacokinetics and Pharmacodynamics: Concepts and Applications, and Essentials of Pharmacokinetics and Pharmacodynamics. He served as an editor of Journal of Pharmacokinetics and Pharmacodynamics (1973-2007), and since 1977 has organised regular residential workshops in pharmacokinetics. He has been awarded honorary doctorate degrees from the Universities of Athens (Greece), Poitiers (France), and Uppsala (Sweden), and Honorary Membership, Royal College of Physicians (London). Despite his retirement, he is still active in the field and a true inspiring mentor to all his (former) students and colleagues. Analogous to professor Ariens, Malcolm Rowland combines basic pharmacological science with clinical concepts.
Ariens award 2019
In 2019, the laureate was Dr. Steven Hill. This Ariens lecture was entitled: “Fluorescent ligand and NanoBRET approaches to study target engagement and ligand-binding kinetics at GPCRs and RTKs”.
Professor Steve Hill is Professor of Molecular Pharmacology in the School of Life Sciences, University of Nottingham. He is also Co-Director of the new University of Birmingham and University of Nottingham Centre of Membrane Proteins and Receptors (COMPARE] and President of the British Pharmacological Society. Steve obtained his first degree in pharmacology at the University of Bristol and his PhD (pharmacology) at the University of Cambridge. His research has concentrated mainly on the molecular pharmacology of cell surface receptors (particularly G protein-coupled receptors [GPCRs] but more recently receptor tyrosine kinases). Currently, the emphasis of his work is on the study of ligand-receptor interactions in membrane microdomains of single living cells using a variety of fluorescent imaging techniques including fluorescence correlation spectroscopy, confocal imaging and resonance energy transfer techniques. In particular, he is interested in the cooperative interactions (positive and negative) between the protomers of receptor dimers, the influence of small molecule allosteric regulators on orthosteric ligand binding and signalling and the potential for protein-protein interactions between receptors and associated signalling proteins to convey signalling bias. He joined the University of Nottingham in 1981 and was subsequently promoted to Reader (1989) and Professor of Molecular Pharmacology (1995). In 1997, he became Director of the Institute of Cell Signalling and in 2008 Head of the School of Biomedical Sciences (until 2013). He was a founding director of the University of Nottingham spin-out company CellAura Technologies Ltd that provided fluorescent ligands to the scientific community until it was acquired by HelloBio in 2014.
His work is currently funded by BBSRC, MRC and the EU ITN ONCORNET. Steve is an Adjunct Professor at the University of Western Australia. He was recently awarded the 2018 Vice Chancellor’s Medal from the University of Nottingham.
Below you will find a link to the list of previous Ariens Awards winners.